What’s Actually in your Vape Juice? Flavorings added to vape juice are FDA approved for consumption, but not inhalation. WebMD shares what's really in your vape and it includes Nicotine, Propylene glycol, Formaldehyde, Glycerin, Lead and Nickel. Nicotine Addiction The amount of nicotine in one standard JUUL pod is roughly equal to the amount of nicotine in a pack of cigarettes, or about 200 puffs. Learn more at the Truth Initiative.